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Clinical trials have mixed results for zetia and vytorin.
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Dosage is based on your medical conditionresponse to treatmentageand other medications you may be takingBe sure to tell your doctor and pharmacist about all the products you useincluding prescription drugsnonprescription drugsand herbal productsChinese patients taking niacin may require lower doses of simvastatinAsk your doctor for more details.
Fenofibrates may increase cholesterol excretion into the bileleading to cholelithiasisIn a preclinical study in dogsezetimibe increased cholesterol in the gallbladder bilesee Animal PharmacologyIf cholelithiasis is suspected in a patient receiving VYTORIN and a fenofibrategallbladder studies are indicated and alternative lipid-lowering therapy should be consideredsee the product labeling for Fenofibrate And Fenofibric Acid
Tell your doctor about all your current medicinesMany drugs can interact with ezetimibe and simvastatinespecially:
The combined use of VYTORIN with gemfibrozilcyclosporineor danazol is contraindicatedsee CONTRAINDICATIONS and DRUG INTERACTIONS
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patients taking amiodarone, amlodipine, or ranolazine should not exceed 10 20 mg, and those taking verapamil or diltiazem should not exceed 10 10 mg of of vytorin daily.