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Linezolid’s mechanism of action differs from those of other antibiotic classesIn vitro studies with clinical isolatesincluding methicillin-resistant staphylococcivancomycin-resistant enterococciand penicillinand erythromycin-resistant streptococciindicate that linezolid is usually active against organisms which are resistant to one or more other classes of antimicrobial agents.
Eating tyramine while you are using linezolid can raise your blood pressure to dangerous levelsAvoid foods that have a high level of tyraminesuch as aged cheeses or meatspickled or fermented meatssmoked or air-dried meatssauerkrautsoy saucetap beerred wineor any meatcheeseor other protein-based food that has been improperly stored.
A history of high blood pressureepilepsy or a history of seizuresdiabetesand you use insulin or an oral diabetes medicationa thyroid disorderkidney or liver diseaseor bone marrow suppression or a weak immune system.
Many drugs can interact with linezolidBefore using this medicinetell your doctor about all other medications you useYou may need to stop using certain medicines before using Zyvoxin some cases for up to 5 weeks before starting treatment
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at both the 600 mg and 1200 mg zyvox doses, no significant effect on qtc interval was detected at peak plasma concentration or at any other time.