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Minimal clinical trialsminimal marketing forceand minimal postmarketing studies.
Read the Medication Guide available from your pharmacist before you start using selegiline and each time you get a refillIf you have any questionsconsult your doctor or pharmacist.
Tell your doctor right away if you have any serious side effectsincludingfaintingmental/mood changese.gagitationconfusionmuscle stiffness/twitchingchanges in sexual ability/interestshakingtremorshiveringswollen ankles/legsunusual weight gain/losseye pain/swelling/rednessvision changese.gdouble/blurred visionsevere stomach/abdominal painpersistent nausea/vomitingseizuresdark urineyellowing eyes/skin.
You should not use an Emsam patch if you have an adrenal gland tumor or if you are using certain other medicinesMany drugs can interact with selegilineand some drugs should not be used together.
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in a dermal carcinogenicity study in cd-1 mice, selegiline the drug substance of emsam was administered daily for 2 years at the same skin site at dose levels of 20, 70, and 200 mg per kg per day dissolved in acetone .