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Elderly subjects may commonly have conditions that may be exacerbated by fludrocortisone therapy includingbut not limited tohypertensionedemahypokalemiacongestive heart failurecataractsglaucomaincreased intraocular pressurerenal insufficiencyand osteoporisissee WARNINGSPRECAUTIONS and ADVERSE REACTIONSElderly subjects may also commonly be taking concomitant drug therapy such as digitalis glycosidesoral anticoagulantsantidiabetic drugsoral agents and insulinand aspirin which may interact with fludrocortisonesee PRECAUTIONSDrug Interactions
Psychic derangements may appear when corticosteroids areusedThese may range from euphoriainsomniamood swingspersonality changesand severe depression to frank psychotic manifestationsExisting emotional instability or psychotic tendencies may also be aggravated by corticosteroids.
Pregnancy and breastfeeding If you are pregnant or breastfeedingthink you may be pregnant or are planning to have a babyask your doctor or pharmacist for advice before taking this medicine.
Infants born of mothers who have received substantial doses of fludrocortisone acetate during pregnancy should be carefully observed for signs of hypoadrenalism.
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