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Patients with a Migraine AttackA migraine attack does not affect the pharmacokinetics of rizatriptan.
Cerebral haemorrhagesubarachnoid haemorrhagestroke and other cerebrovascular events have been reported in patients treated with 5-HT 1 agonistsand some have resulted in fatalitiesIn a number of casesit appears possible that the cerebrovascular events were primarythe agonist having been administered in the incorrect belief that the symptoms experienced were a consequence of migrainewhen they were notIt should be noted that patients with migraine may be at increased risk of certain cerebrovascular eventse.gstrokehaemorrhagetransient ischaemic attack
Make changes in your diet such as avoid such foodsincluding caffeine and alcohol which are believed to trigger headachesYou can also try muscle relaxation exercisesyoga or meditation to ease the migraine attack.
Rizatriptan should only be used where a clear diagnosis of migraine has been establishedRizatriptan should not be administered to patients with basilar or haemiplegic migraineAs with other 5-HT 1B1D agonistssensations of tightnesspainpressure and heaviness have been reported after treatment with rizatriptan in the precordiumthroatneck and jawThese events have not been associated with arrhythmias or definite ischaemic electrocardiogramECGchanges in clinical trialsone patient experienced chest pain with possible ischaemic ECG changesBecause drugs in this class may cause coronary artery vasospasmpatients who experience signs or symptoms suggestive of angina following dosing should be evaluated for the presence of coronary artery diseaseCADor a predisposition to Prinzmetal’s variant angina before receiving additional doses of medicationand should be monitored by ECG if dosing is resumed and similar symptoms recurSimilarlypatients who experience other symptoms or signs suggestive of decreased arterial flowsuch as ischaemic bowel syndrome or Raynaud’s syndrome following the use of any 5-HT 1 agonist are candidates for further evaluation.
Angio-oedemae.gfacial oedematongue swelling and pharyngeal oedemamay occur in patients treated with triptanssuch as rizatriptanIf angio-oedema of the tongue or pharynx occursthe patient should be placed under medical supervision until the symptoms have resolvedTreatment should promptly be discontinued and replaced by an agent belonging to another class of drugs.
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rizact orodispersible disintegrating tablets 5mg contain rizatriptan, which is a seroton.