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In US placebo-controlled clinical trials of fluoxetine for other approved indicationschanges in appetite and weight have also been reportedsee ADVERSE REACTIONS Table 5
Table 2Altered Appetite and Weight Treatment Emergent Adverse ReactionsIncidence in PMDD Placebo-Controlled Clinical Trials.
The pupillary dilation that occurs following use of many antidepressants and SARAFEM may trigger an angle closure attack in a patient with anatomically narrow angles who does not have a patent iridectomy.
The effect of fluoxetine on labor and delivery in humans is unknownHoweverbecause fluoxetine crosses the placenta and because of the possibility that fluoxetine may have adverse effects on the newbornfluoxetine should be used during labor and delivery only if the potential benefit justifies the potential risk to the fetus.
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