Sulfamethoxazole; trimethoprim, smx-tmp, cotrimoxazole minor sulfonamides may compete with penicillin for renal tubular secretion, increasing penicillin serum concentrations.
Severe skin reactionfeversore throatswelling in your face or tongueburning in your eyesskin painfollowed by a red or purple skin rash that spreadsespecially in the face or upper bodyand causes blistering and peeling.
These are not all of the side effects that may occurIf you have questions about side effectscall your doctorCall your doctor for medical advice about side effects.
Using this medicine with any of the following medicines may cause an increased risk of certain side effectsbut using both drugs may be the best treatment for youIf both medicines are prescribed togetheryour doctor may change the dose or how often you use one or both of the medicines.
Allergic reactions like skin rashitching or hivesswelling of the facelipsor tongue breathing problems dark urine rednessblisteringpeeling or loosening of the skinincluding inside the mouth diarrhea stomach upset headache dizziness trouble sleeping seizures unusually weak or tired unusual bleeding or bruising yellowing of the eyes or skin trouble passing urineor a decrease in the quantity of urine.
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cloxacillin and cephalexin were preferred for mild infection, while amoxicillin with clavulinic acid and cotrimoxazole with metronidazole were preferred for moderate infection.